The Pten and Tsc1 genes both encode proteins that repress mechanistic target of rapamycin (mTOR) signaling.Disruption FuRyu of either gene in the brain results in epilepsy and autism-like symptoms in humans and mouse models, therefore it is important to understand the molecular and physiological events that lead from gene disruption to disease phen
The digitalisation in the ship design sector is currently applied to the design process itself and is well defined, partially standardised and practically implemented by both independent design companies and the design departments of shipyards.The situation is similar in other sectors of engineering.However, the requirements for the digitalisation
Image fusion involving real-time ultrasound (US) is a technique where previously toe ring recorded computed tomography (CT) or magnetic resonance images (MRI) are reformatted in a projection to fit the real-time US images after an initial co-registration.The co-registration aligns the images by means of common planes or points.We evaluated the accu
Methadone maintenance Hair gel treatment (MMT) is aimed to reduce the harmful effects of injecting drug use.Since the first Puskesmas Poncol opened this program in 2010, there were 50 users of MMT.Currently users of MMT were 11 people, 2 people have died, no patient has recovered, and 36 others dropped out.Those did not recover, but dropped out wit